Compounds / Cosmetic / SNAP-8

SNAP-8

SNAP-8 (Acetyl Octapeptide-3 — Anti-Wrinkle Cosmeceutical)

CosmeticWell ResearchedFDA: Not approved (cosmetic ingredient)

Overview

Primarily studied as cosmeceutical ingredient for wrinkle reduction. Anti-wrinkle efficacy in clinical cosmetic trials. SQ research route for systemic dermal effects.

Mechanism of Action

Extended Argireline analog. Competitively inhibits SNAP-25 in SNARE complex. Attenuates acetylcholine release at neuromuscular junctions → facial muscle relaxation without paralysis. Botulinum toxin-like mechanism via SNARE inhibition.

Molecular Profile

Molecular weight

1,075.16 Da

Type

Acetylated octapeptide with C-terminal amidation

Length

8 amino acids

Key Research Findings

SNARE complex inhibition; acetylcholine reduction; wrinkle reduction; non-paralytic mechanism.

Published Research

J Anal Sci Technol (2020)

Kim S et al. Method development for acetyl octapeptide-3 (SNAP-8) analysis by LC-MS/MS (analytical characterization; efficacy data is manufacturer-reported, not peer-reviewed)

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Related Cosmetic Compounds

Glow Protocol

Clinical Guidance

Research data is not a treatment plan. If you are considering SNAP-8, the questions that matter are whether it suits your history, your labs and your goals. That is a conversation with a licensed physician, not a lookup.

Speak with a physician LATOM Wellness is a physician-led telehealth practice. Consultation only. No compound is sold on this site.

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Interactive tools for this compound:

Reconstitution calculator · Full deep dive · Peptide fundamentals