Compounds / Cognitive / Cerebrolysin

Cerebrolysin

Cerebrolysin (Porcine Brain-Derived Neuropeptide Preparation)
CognitiveWell ResearchedFDA: Not approved (approved in 50+ countries...

Overview

Clinical use in Eastern Europe/Asia for stroke, TBI, dementia. Evidence: strong for vascular dementia and TBI; mixed for Alzheimer's. IV use in clinical settings. SQ research use.

Mechanism of Action

Low-molecular-weight neuropeptides mimicking endogenous neurotrophic factors (NGF, BDNF, CNTF). Crosses BBB. Modulates neuroinflammation. Neuroprotective and neurotrophic. Anti-apoptotic in injured neurons.

Pharmacokinetics

Half-life
1 hr
Peak (Tmax)
30 min
Cleared
~5 hrs

Molecular Profile

Molecular weight
<10,000 Da (peptide mixture)

Key Research Findings

BBB-crossing neuropeptides; vascular dementia evidence; TBI strong evidence; Alzheimer's mixed.

Published Research

Brain Inj (2019)
Ghaffar O et al. Cerebrolysin for TBI: systematic review and meta-analysis
View source

Related Cognitive Compounds

SemaxNA Semax AmidateSelankAdalankAdamaxDihexa
Clinical Guidance

Research data is not a treatment plan. If you are considering Cerebrolysin, the questions that matter are whether it suits your history, your labs and your goals. That is a conversation with a licensed physician, not a lookup.

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Interactive tools for this compound:

Reconstitution calculator  ·  Full deep dive  ·  Peptide fundamentals