Compounds / Cognitive / Cyclic Glycine-Proline (cGP)

Cyclic Glycine-Proline (cGP)

Cyclic Glycine-Proline (cGP — IGF-1 Bioavailability Regulator)
CognitiveEmerging ResearchFDA: Not approved; emerging research

Overview

Emerging research from New Zealand/Auckland group. Endogenous metabolite of IGF-1 pro-peptide. Neuroprotection and IGF-1 regulation research.

Mechanism of Action

Cyclic dipeptide. Regulates IGF-1 bioavailability by modulating IGF binding proteins. Neuroprotective. May enhance IGF-1 transport across BBB. Anti-inflammatory. Cardiovascular support.

Molecular Profile

Molecular weight
154.17 Da
Type
Cyclic dipeptide (2,5-diketopiperazine)
Length
2 amino acids
cyclo(Gly-Pro)

Key Research Findings

IGF-1 bioavailability regulation; neuroprotection; anti-inflammatory; BBB transport.

Published Research

Sci Rep (2014)
Guan J et al. Peripheral cyclic glycine-proline regulates IGF-1 function
View source

Related Cognitive Compounds

SemaxNA Semax AmidateSelankAdalankAdamaxDihexa
Clinical Guidance

Research data is not a treatment plan. If you are considering Cyclic Glycine-Proline (cGP), the questions that matter are whether it suits your history, your labs and your goals. That is a conversation with a licensed physician, not a lookup.

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