Compounds / GH Axis / GHRP-6

GHRP-6

GHRP-6 (Growth Hormone-Releasing Peptide 6 — Hexapeptide)

GH AxisFDA: Not approvedWADA: PROHIBITED — Category S2

Overview

First GH secretagogue extensively studied in humans. Appetite stimulation limits clinical use. Half-life ~2.5 hours requires 3× daily dosing for optimal GH elevation.

Mechanism of Action

GHS-R1a agonist + ghrelin receptor. Notable APPETITE STIMULATION via ghrelin pathway — major differentiator from Ipamorelin and GHRP-2. GH release potency high but hunger-stimulating side effect is significant.

Molecular Profile

Molecular weight

873.0 Da

CAS number

87616-84-0

Key Research Findings

Potent GH release; APPETITE STIMULATION (clinical consideration); 3× daily dosing; ghrelin pathway.

Published Research

J Clin Endocrinol Metab (1994)

Bowers CY et al. A novel compound increases GH release by a pituitary mechanism

View source

Related GH Axis Compounds

Ipamorelin CJC-1295 (No DAC)CJC-1295 (DAC)Sermorelin Tesamorelin GHRP-2

Clinical Guidance

Research data is not a treatment plan. If you are considering GHRP-6, the questions that matter are whether it suits your history, your labs and your goals. That is a conversation with a licensed physician, not a lookup.

Speak with a physician LATOM Wellness is a physician-led telehealth practice. Consultation only. No compound is sold on this site.

Running GHRP-6? Log doses and track your cycle.

Interactive tools for this compound:

Reconstitution calculator · Full deep dive · Peptide fundamentals