Compounds / Tissue Repair / BPC-157

BPC-157

Body Protection Compound-157
Tissue RepairExtensively StudiedFDA: Not approved; investigationalWADA: PROHIBITED (S0 — added 2022)

Overview

Preclinical: accelerated wound repair in gut, tendon, ligament, muscle. Phase I oral safety trial completed (NCT02637284). Limited human data.

Mechanism of Action

Modulates NO/VEGF/EGF pathways. Promotes angiogenesis, collagen deposition, cytoprotection. FAK-paxillin pathway activation for cell migration. GI mucosal protection.

Pharmacokinetics

Half-life
4 hrs
Peak (Tmax)
1 hr
Cleared
~20 hrs

Molecular Profile

Molecular weight
1,419.53 Da
CAS number
137525-51-0
Type
Pentadecapeptide
Length
15 amino acids
Gly-Lys-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Key Research Findings

Tendon-to-bone healing; GI cytoprotection; anti-inflammatory; angiogenesis.

Published Research

Curr Pharm Des (PMC)
Sikiric P et al. BPC-157: novel therapy for wound healing
View source
J Orthop Res
Chang CH et al. BPC-157 promotes tendon-to-bone healing
View source
ClinicalTrials.gov
NCT02637284: Phase I safety trial of oral BPC-157
View source

Related Tissue Repair Compounds

TB-500AHK-CuKPVMGFPEG-MGFKLOW Protocol
Clinical Guidance

Research data is not a treatment plan. If you are considering BPC-157, the questions that matter are whether it suits your history, your labs and your goals. That is a conversation with a licensed physician, not a lookup.

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Interactive tools for this compound:

Reconstitution calculator  ·  Full deep dive  ·  Peptide fundamentals