Compounds / Tissue Repair / PEG-MGF

PEG-MGF

PEGylated Mechano Growth Factor (PEG-MGF)
Tissue RepairLimited ResearchFDA: Not approvedWADA: PROHIBITED — Category S2

Overview

Extended-action MGF variant. Systemic muscle repair support. More practical dosing than native MGF due to extended half-life.

Mechanism of Action

PEGylation extends MGF half-life from minutes to ~72 hours, enabling systemic distribution vs local MGF. Same satellite cell activation mechanism as native MGF but sustained action.

Molecular Profile

Molecular weight
~4500 Da (with PEG)
Type
IGF-1Ec splice variant C-terminal peptide
Length
24 amino acids
YQPPSTNKNTKSQRRKGSTFEEHK

Key Research Findings

Extended half-life (~72h vs minutes for MGF); systemic distribution; satellite cell activation.

Published Research

FASEB J (2005)
Dluzniewska J et al. A strong neuroprotective effect of the autonomous C-terminal domain of IGF-1 (E peptide) in brain ischemia
View source

Related Tissue Repair Compounds

BPC-157TB-500AHK-CuKPVMGFKLOW Protocol
Clinical Guidance

Research data is not a treatment plan. If you are considering PEG-MGF, the questions that matter are whether it suits your history, your labs and your goals. That is a conversation with a licensed physician, not a lookup.

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Running PEG-MGF? Log doses and track your cycle.

Interactive tools for this compound:

Reconstitution calculator  ·  Full deep dive  ·  Peptide fundamentals